Human Dedicator of Cytokinesis Protein 1, DOCK1 ELISA Kit

SKU: E5173Hu

Size:96 Tests-1 Kit

Background:Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed: 19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed: 8657152).

Research_area:Others

Applications:ELISA

Target_protein:DOCK1

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.72ng/L

Detection range:20-6000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Dedicator of Cytokinesis Protein 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q14185

MASS(Da):215,346

GeneID:1793

Synonyms:180 kDa protein downstream of CRK;Dedicator of cytokinesis protein 1;DOCK 1;DOCK1;DOCK180

Gene names:DOCK1

Standard solution:6400ng/L