Human Cytochrome Coxidase Assembly Protein Cox15 Homolog, COX15 ELISA Kit

SKU: E6759Hu

Size:96 Tests-1 Kit

Background:Cytochrome c oxidase assembly protein COX15 homolog (COX15), also known as heme A synthase, is a protein that in humans is encoded by the COX15 gene. This protein localizes to the inner mitochondrial membrane and involved in heme A biosynthesis.COX15 is also part of a three-component mono-oxygenase (ferredoxin, ferredoxin reductase, and COX15) that catalyses the hydroxylation of the methyl group at position eight of the protoheme molecule. Mutations in this gene has been reported in patients with hypertrophic cardiomyopathy as well as Leigh syndrome, and characterized by delayed onset of symptoms, hypotonia, feeding difficulties, failure to thrive, motor regression, and brain stem signs.

Research_area:Signal Transduction; Metabolism

Applications:ELISA

Target_protein:COX15

Reactivity:Human

Assay type:Sandwich

Sensitivity:11.28ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Cytochrome c oxidase assembly protein COX15 homolog

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q7KZN9

MASS(Da):46,030

GeneID:1355

Synonyms:CEMCOX2;COX15;Cytochrome c oxidase assembly protein COX15 homolog;MC4DN6

Gene names:COX15

Standard solution:4800ng/L