Human CXCL11/I-TAC ELISA Kit PicoKine®

SKU: EK0737

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CXCL11

Specificity: Natural and recombinant human CXCL11

Background: Chemokine (C-X-C motif) ligand 11 (CXCL11) is a small cytokine belonging to the CXC chemokine family that is also called Interferon-inducible T-cell alpha chemoattractant (I-TAC) and Interferon-gamma-inducible protein 9 (IP-9). By PCR analysis of somatic cell hybrids, the CXCL11 gene was mapped to chromosome 4, and using FISH, it was located to 4q21.2. The CXCL11 was strongly induced by IFNG and beta-interferon, but only weakly induced by alpha-interferon. Induction of CXCL11 required expression of STAT1. What's more, it found that monocyte chemotaxis occurs in response to recombinant CXCL11. RT-PCR analysis detected CXCL11 expression in brain tissue from a patient with AIDS dementia and a patient with multiple sclerosis but not in 2 controls.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: F22-F94

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Reference:

Uniprot ID: O14625

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 6373

Protein Name: C-X-C motif chemokine 11

Gene Full Name: C-X-C motif chemokine ligand 11

Synonyms: b R1; Beta R1; C X C motif chemokine 11; CXCL11; H174; I TAC; IP 9; IP9; ITAC; SCYB11; SCYB9B; Small inducible cytokine B11