Human Corin ELISA Kit PicoKine®

SKU: EK1283

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CORIN

Specificity: Natural and recombinant human Corin

Background: Atrial natriuretic peptide-converting enzyme, also called CRN or ATC2, is a protein that in humans is encoded by the CORIN gene. It is mapped to 4p12. This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. It has been found that Corin is the pro-ANP-converting enzyme and that Corin-mediated pro-ANP activation may play a role in regulating blood pressure. What’s more, Corin and ANP are essential for physiologic changes at the maternal-fetal interface. This protein may also function as a pro-brain-type natriuretic peptide convertase. Corin gene mutations which cause Corin to impair activity might be an underlying mechanism in hypertension.

Immunogen: Expression system for standard: NS0; Immunogen sequence: S67-N1042

Clonality:

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Reconstitution:

Reference:

Uniprot ID: Q9Y5Q5

Host:

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Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Calculated Molecular Weight:

Gene ID: 10699

Protein Name: Atrial natriuretic peptide-converting enzyme

Gene Full Name: corin, serine peptidase

Synonyms: CORIN; CRN; TMPRSS10; ATC2; Lrp4; PEE5