Human complement C3a EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ2145

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: C3

Specificity: Natural and recombinant human C3

Background: Complement component 3, often simply called C3, is a protein of the immune system. In humans it is encoded on chromosome 19 by a gene called C3. Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: S672-R748

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Reference:

Uniprot ID: P01024

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 718

Protein Name: Complement C3

Gene Full Name: complement C3

Synonyms: ARMD9; ASP; C3; C3b; C3c; Complement C3; complement component 3; CPAMD1