Human collectin sub-family member 11,COLEC11 ELISA KIT

SKU: E1907Hu

Size:96 Tests-1 Kit

Background:Lectin that plays a role in innate immunity, apoptosis and embryogenesis (PubMed:23954398, PubMed:25912189, PubMed:21258343). Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope (PubMed:25912189). Primarily recognizes the terminal disaccharide of the glycan (PubMed:25912189). Also recognizes a subset of fucosylated glycans and lipopolysaccharides (PubMed:17179669, PubMed:25912189). Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1 (PubMed:20956340, PubMed:25912189). Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding (Probable). Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis (PubMed:21258343, PubMed:28301481). {ECO:0000269|PubMed:17179669, ECO:0000269|PubMed:20956340, ECO:0000269|PubMed:21258343, ECO:0000269|PubMed:23954398, ECO:0000269|PubMed:25912189, ECO:0000269|PubMed:28301481, ECO:0000305|PubMed:20956340, ECO:0000305|PubMed:23954398}.

Research_area:

Applications:ELISA

Target_protein:COLEC11

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.05ng/ml

Detection range:0.1-6.4ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:collectin sub-family member 11

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9BWP8

MASS(Da):28665

GeneID:78989

Synonyms:COLEC11 UNQ596/PRO1182

Gene names:COLEC11

Standard solution:12.8ng/ml