Human Coatomer Subunit Alpha, COPA ELISA Kit

SKU: E6842Hu

Size:96 Tests-1 Kit

Background:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). Xenin stimulates exocrine pancreatic secretion. It inhibits pentagastrin-stimulated secretion of acid, to induce exocrine pancreatic secretion and to affect small and large intestinal motility. In the gut, xenin interacts with the neurotensin receptor.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:COPA

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.094ng/ml

Detection range:0.2-60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Coatomer subunit Alpha

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P53621

MASS(Da):138,346

GeneID:1314

Synonyms:AILJK;Alpha-coat protein;alpha-COP;Coatomer subunit alpha;COPA;HEPCOP;HEP-COP;Proxenin];Xenin;Xenopsin-related Peptide

Gene names:COPA

Standard solution:64ng/ml