Human CNTFR ELISA Kit PicoKine®

SKU: EK2170

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CNTFR

Specificity: Natural and recombinant Human CNTFR

Background: The ciliary neurotrophic factor receptor, also known as CNTFR, binds the ciliary neurotrophic factor. This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q23-S342

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Reconstitution:

Reference:

Uniprot ID: P26992

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 1271

Protein Name: Ciliary neurotrophic factor receptor subunit alpha

Gene Full Name: ciliary neurotrophic factor receptor

Synonyms: CNTF receptor subunit alpha; CNTFR; CNTFR alpha