Human Cleavage and Polyadenylation Specific Factor 1, CPSF1 ELISA Kit

SKU: E2465Hu

Size:96 Tests-1 Kit

Background:Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (PubMed: 14749727). May play a role in eye morphogenesis and the development of retinal ganglion cell projections to the midbrain (By similarity).

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:CPSF1

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.46ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Cleavage and Polyadenylation Specific Factor 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q10570

MASS(Da):160,884

GeneID:29894

Synonyms:Cleavage and polyadenylation specificity factor 160 kDa subunit;Cleavage and polyadenylation specificity factor subunit 1;CPSF 1;CPSF 160 kDa subunit;CPSF1

Gene names:CPSF1

Standard solution:2400ng/L