Human Cgmp-dependent Protein Kinase 2, PRKG2 ELISA Kit

SKU: E5035Hu

Size:96 Tests-1 Kit

Background:Crucial regulator of intestinal secretion and bone growth (By similarity). Phosphorylates and activates CFTR on the plasma membrane. Plays a key role in intestinal secretion by regulating cGMP-dependent translocation of CFTR in jejunum (By similarity). Acts downstream of NMDAR to activate the plasma membrane accumulation of GRIA1/GLUR1 in synapse and increase synaptic plasticity. Phosphorylates GRIA1/GLUR1 at Ser-863 (By similarity). Acts as regulator of gene expression and activator of the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2 in mechanically stimulated osteoblasts. Under fluid shear stress, mediates ERK activation and subsequent induction of FOS, FOSL1/FRA1, FOSL2/FRA2 and FOSB that play a key role in the osteoblast anabolic response to mechanical stimulation (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:PRKG2

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.31ng/L

Detection range:20-3800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Cgmp-Dependent Protein Kinase 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q13237

MASS(Da):87,432

GeneID:5593

Synonyms:cGK 2;cGK2;cGKII;cGMP-dependent protein kinase 2;cGMP-dependent protein kinase II;PRKG 2;PRKG2

Gene names:PRKG2

Standard solution:4000ng/L