Human Cd59 Glycoprotein, CD59 ELISA Kit

SKU: E4730Hu

Size:96 Tests-1 Kit

Background:Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.

Research_area:Immunology

Applications:ELISA

Target_protein:CD59

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.23ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Cd59 Glycoprotein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P13987

MASS(Da):14,177

GeneID:966

Synonyms:1F5 antigen;20 kDa homologous restriction factor;CD 59;CD antigen CD59;CD59;CD59 glycoprotein;HRF20;HRF-20;MACIF;MAC-inhibitory protein;MAC-IP;MEM43 antigen;Membrane attack complex inhibition factor;Membrane inhibitor of reactive lysis;MIRL;Protectin

Gene names:CD59

Standard solution:2400ng/L