Human Cd320 Antigen, CD320 ELISA Kit

SKU: E7000Hu

Size:96 Tests-1 Kit

Background:Receptor for transcobalamin saturated with cobalamin (TCbl) (PubMed: 18779389). Plays an important role in cobalamin uptake (PubMed: 18779389, PubMed: 20524213). Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells (PubMed: 10727470). Functions as costimulator to promote B cell responses to antigenic stimuli; promotes B cell differentiation and proliferation (PubMed: 10727470, PubMed: 11418631). Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC) (PubMed: 11418631). CD320 augments the proliferation of PC precursors generated by IL-10 (PubMed: 11418631).

Research_area:Others

Applications:ELISA

Target_protein:CD320

Reactivity:Human

Assay type:Sandwich

Sensitivity:8.25mg/L

Detection range:20-4500mg/L

Sample type:Serum, plasma or other biological fluids

Full product name:CD320 Antigen

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9NPF0

MASS(Da):28,991

GeneID:51293

Synonyms:8D6 antigen;CD 320;CD antigen CD320;CD320;CD320 antigen;FDC-signaling molecule 8D6;FDC-SM-8D6;TCblR;Transcobalamin receptor;

Gene names:CD320

Standard solution:4800mg/L