Human CD21/CR2 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ1315

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CR2

Specificity: Natural and recombinant human CD21

Background: Complement receptor type 2 (CR2), also known as C3DR or CD21, is a protein that in humans is encoded by the CR2 gene. It is mapped to 1q32.2. CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. CR2 is the membrane protein on B lymphocytes to which the Epstein-Barr virus (EBV) binds during infection of these cells. CR2, together with CD19, CD81, and CD225, forms the B-cell coreceptor complex, which lowers the activation threshold of the B-cell antigen receptor. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9).

Immunogen: Expression system for standard: CHO; Immunogen sequence: Ile21-71

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Uniprot ID: P20023

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 1380

Protein Name: Complement receptor type 2

Gene Full Name: complement C3d receptor 2

Synonyms: C3DR; CD21; Complement C3d receptor; Complement receptor type 2; CR2; EBV receptor; Epstein Barr virus receptor; SLEB9