Human CCL14/HCC-1 PicoKine® Quick ELISA Kit

SKU: FEK1123

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CCL14

Specificity: Natural and recombinant human CCL14

Background: Chemokine(C-C motif) ligand 14(CCL14) is a small cytokine belonging to the CC chemokine family. It is also commonly known as HCC-1. It is produced as a protein precursor that is processed to generate a mature active protein containing 74 amino acids that and is 46% identical in amino acid composition to CCL3 and CCL4. This chemokine is expressed in various tissues including spleen, bone marrow, liver, muscle, and gut. CCL14 activates monocytes, but does not induce their chemotaxis. In addition, HCC-1 enhanced the proliferation of CD34+ myeloid progenitor cells. It was as effective as MIP-1 alpha, but about 100-fold less potent. Human CCL14 is located on chromosome 17 within a cluster of other chemokines belonging to the CC family.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: T20-N93

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Reference:

Uniprot ID: Q16627

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 6358

Protein Name: C-C motif chemokine 14

Gene Full Name: C-C motif chemokine ligand 14

Synonyms: C C motif chemokine 14; CC 1; CC 3; CCL14; Chemokine CC 1/CC 3; CKb1; HCC 1; HCC 1(1 74); HCC 1/HCC 3; HCC 3; MCIF; NCC 2; NCC2; SCYA14; SCYL2; Small inducible cytokine A14; SY14