Human Carbohydrate Sulfotransferase 15, CHST15 ELISA Kit

SKU: E2872Hu

Size:96 Tests-1 Kit

Background:Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO4) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.

Research_area:Immunology

Applications:ELISA

Target_protein:CHST15

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.043ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Carbohydrate Sulfotransferase 15

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q7LFX5

MASS(Da):64,926

GeneID:51363

Synonyms:B-cell RAG-associated gene protein;BRAG;Carbohydrate sulfotransferase 15;CHST15;GALNAC4S-6ST;hBRAG;N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase

Gene names:CHST15

Standard solution:48ng/ml