Human CA125/MUC16 ELISA Kit PicoKine®

SKU: EK1471

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: MUC16

Specificity: Natural and recombinant human CA125

Background: CA-125, also known as mucin 16 or MUC16, is a protein that in humans is encoded by the MUC16 gene. MUC16 is a member of the mucin family glycoproteins. It is a component of the ocular surface, the respiratory tract and the female reproductive tract epithelia. Since MUC16 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells. Also, the cytoplasmic tail of MUC16 has been shown to interact with cytoskeleton by binding members of the ERM protein family. The expression of mucin 16 has been shown to be altered in dry eye, cystic fibrosis, and several types of cancers.

Immunogen: natural protein

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Reference:

Uniprot ID: Q8WXI7

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 94025

Protein Name: Mucin-16

Gene Full Name: mucin 16, cell surface associated

Synonyms: CA 125; CA125; MUC 16; MUC16; MUC16; CA125; Mucin 16