Human C-type Mannose Receptor 2, MRC2 ELISA Kit

SKU: E5136Hu

Size:96 Tests-1 Kit

Background:May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).

Research_area:Cell Biology

Applications:ELISA

Target_protein:MRC2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.046ng/ml

Detection range:0.1-40ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:C-type mannose receptor 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9UBG0

MASS(Da):166,674

GeneID:9902

Synonyms:CD antigen CD280;CD280;CLEC13E;C-type lectin domain family 13 member E;C-type mannose receptor 2;ENDO180;Endocytic receptor 180;Macrophage mannose receptor 2;MRC2;UPARAP;UPAR-associated protein;Urokinase receptor-associated protein;Urokinase-type plasminogen activator receptor-associated protein;

Gene names:MRC2

Standard solution:48ng/ml