Human C-type Lectin Domain Family 7 Member A, CLEC7A ELISA Kit

SKU: E4020hu

Size:96 Tests-1 Kit

Background:Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Induces phosphorylation of SCIMP after binding beta-glucans (By similarity). Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity).

Research_area:Immunology

Applications:ELISA

Target_protein:CLEC7A

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.14ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:C-Type Lectin Domain Family 7 Member A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9BXN2

MASS(Da):27,627

GeneID:64581

Synonyms:Beta-glucan receptor;CD antigen CD369;CLEC7A;C-type lectin domain family 7 member A;C-type lectin superfamily member 12;DC-associated C-type lectin 1;Dectin-1;Dendritic cell-associated C-type lectin 1

Gene names:CLEC7A

Standard solution:4800ng/L