Human Brca1-associated Protein, BRAP ELISA Kit

SKU: E6565Hu

Size:96 Tests-1 Kit

Background:Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:BRAP

Reactivity:Human

Assay type:Sandwich

Sensitivity:10.09ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Brca1-Associated Protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q7Z569

MASS(Da):67,305

GeneID:8315

Synonyms:BRAP;BRAP2;BRCA1-associated protein;IMP;Impedes mitogenic signal propagation;Renal carcinoma antigen NY-REN-63;RING finger protein 52;RING-type E3 ubiquitin transferase BRAP2

Gene names:BRAP

Standard solution:4800ng/L