Human Bone Morphogenetic Protein 10, BMP10 ELISA Kit

SKU: E2241Hu

Size:96 Tests-1 Kit

Background:Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

Research_area:Signal Transduction; Cardiovascular

Applications:ELISA

Target_protein:BMP10

Reactivity:Human

Assay type:Sandwich

Sensitivity:11.22ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Bone Morphogenetic Protein 10

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O95393

MASS(Da):48,047

GeneID:27302

Synonyms:BMP 10;BMP10;BMP-10;Bone morphogenetic protein 10

Gene names:BMP10

Standard solution:4800ng/L