Human B-cell Differentiation Antigen CD72, CD72 ELISA Kit

SKU: E6538Hu

Size:96 Tests-1 Kit

Background:CD27 is a member of the tumor necrosis factor receptor superfamily. It is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule, and is the target of an anti-cancer drug in clinical trials. During mouse embryonic development, specific (medium) expression levels of CD27 (in addition to high cKit, medium Gata2, and high CD31 expression levels) define the very first adult definitive hematopoietic stem cells generated in the aorta-gonad-mesonephros region. Furthermore, CD27 is expressed on both naïve and activated effector T cells as well as NK cells and activated B cells. It is a type I transmembrane protein with cysteine-rich domains, but once T cells have become activated, a soluble form of CD27 can be shed.

Research_area:Immunology; Stem Cells

Applications:ELISA

Target_protein:CD72

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.25ng/ml

Detection range:0.5-100ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:B-cell differentiation antigen CD72

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P21854

MASS(Da):40,220

GeneID:971

Synonyms:B-cell differentiation antigen CD72;CD antigen CD72;CD72;CD72b;LYB2;Lyb-2

Gene names:CD72

Standard solution:128ng/ml