Human Aquaporin 4, AQP-4 ELISA Kit

SKU: E0616Hu

Size:96 Tests-1 Kit

Background:Forms a water-specific Channel (PubMed: 7559426, PubMed: 8601457, PubMed: 19383790). Plays an important role in brain water homeostasis and in glymphatic solute transport. Required for a normal rate of water exchange across the blood brain interface. Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways. Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid Peptides derived from APP. Plays a redundant role in urinary water homeostasis and urinary concentrating ability (By similarity).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:AQP4

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.022ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Aquaporin 4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P55087

MASS(Da):34,830

GeneID:361

Synonyms:AQP 4;AQP4;AQP-4;Aquaporin-4;Mercurial-insensitive water Channel;MIWC;WCH4

Gene names:AQP4

Standard solution:24ng/ml