Human APOE/Apolipoprotein E ELISA Kit PicoKine®

SKU: EK1455

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: APOE

Specificity: Natural human APOE

Background: Apolipoprotein E (APOE) is a class of apolipoprotein found in the chylomicron and Intermediate-density lipoprotein (IDLs) that is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. In peripheral tissues, APOE is primarily produced by the liver and macrophages, and mediates cholesterol metabolism in an isoform- dependent manner. In the central nervous system, APOE is mainly produced by astrocytes, and transports cholesterol to neurons via APOE receptors, which are members of the low density lipoprotein receptor gene family. This protein is involved in Alzheimer’s disease and cardiovascular disease.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: K19-H317

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Reference:

Uniprot ID: P02649

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 348

Protein Name: Apolipoprotein E

Gene Full Name: apolipoprotein E

Synonyms: AD2; Apo E; APOE; apoe4; apolipoprotein E; LPG; apolipoprotein E3