Human APOA1/Apolipoprotein A-I PicoKine® Quick ELISA Kit

SKU: FEK1456

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: APOA1

Specificity: Natural and recombinant Human APOA1

Background: Apolipoprotein A1 is a protein that in humans is encoded by the APOA1 gene. This gene encodes apolipoprotein A-I, which is the major protein component of high absorbance lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: D25-Q267

Clonality:

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Reference:

Uniprot ID: P02647

Host:

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 335

Protein Name: Apolipoprotein A-I

Gene Full Name: apolipoprotein A1

Synonyms: Apo AI; ApoA I; APOA1; apolipoprotein A I; Apolipoprotein A1