Human ADAMTS13 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

SKU: EZ0927

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: ADAMTS13

Specificity:

Background: ADAMTS13 is a zinc-containing metalloprotease enzyme. The ADAMTS13 gene is mapped to chromosome 9q34 by genomic sequence analysis. It is reported that a metal-containing proteolytic enzyme (metalloprotease) in normal plasma cleaves the peptide bond between tyrosine at position 842 and methionine at position 843 in monomeric subunits of von Willebrand factor, thereby degrading the large multimers. And it is confirmed that the ADAMTS13 gene encodes the von Willebrand factor-cleaving protease (VWFCP). ADAMTS13 is secreted in blood and degrades large vWf multimers, decreasing their activity.

Immunogen: Expression system for standard: CHO; Immunogen sequence: Q34-W688

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Reconstitution:

Reference:

Uniprot ID: Q76LX8

Host:

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Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 11093

Protein Name: A disintegrin and metalloproteinase with thrombospondin motifs 13

Gene Full Name: ADAM metallopeptidase with thrombospondin type 1 motif 13

Synonyms: ADAM TS 13; ADAM TS13; ADAMTS 13; ADAMTS13; C9orf8; DKFZp434C2322; FLJ42993; TTP; vWF cleaving protease; vWF CP; VWFCP