Human Activin receptor-like kinase 1,ALK1 ELISA KIT

SKU: E0711Hu

Size:96 Tests-1 Kit

Background:Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. {ECO:0000269|PubMed:22718755, ECO:0000269|PubMed:22799562, ECO:0000269|PubMed:26176610}.

Research_area:

Applications:ELISA

Target_protein:ACVRL1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.23ng/ml

Detection range:0.5-150ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Activin receptor-like kinase 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P37023

MASS(Da):56124

GeneID:94

Synonyms:ACVRL1 ACVRLK1 ALK1

Gene names:ACVRL1

Standard solution:160ng/ml