Human Acid Sphingomyelinase-like Phosphodiesterase 3B, SMPDL3B ELISA Kit

SKU: E4893Hu

Size:96 Tests-1 Kit

Background:Lipid-modulating phosphodiesterase (PubMed: 26095358). Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling (By similarity). Has in vitro phosphodiesterase activity, but the physiological substrate is unknown (PubMed: 26095358). Lacks activity with phosphocholine-containing lipids, but can cleave CDP-choline, and can release phosphate from ATP and ADP (in vitro) (By similarity).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:SMPDL3B

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.14ng/mL

Detection range:0.3-90ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Acid Sphingomyelinase-Like Phosphodiesterase 3B

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q92485

MASS(Da):50,814

GeneID:27293

Synonyms:Acid sphingomyelinase-like phosphodiesterase 3b;ASM-like phosphodiesterase 3b;SMPDL3B

Gene names:SMPDL3B

Standard solution:96ng/mL