Human A Disintegrin and Metalloproteinase with Thrombospondin Motifs 6, ADAMTS6 ELISA Kit

SKU: E3480Hu

Size:96 Tests-1 Kit

Background:ADAM metallopeptidase with thrombospondin type 1 motif 6 is a protein that in humans is encoded by the ADAMTS6 gene. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Expression of this gene may be regulated by the cytokine TNF-alpha. Mutation in ADAMTS6 causes predisposition to hernias.

Research_area:Signal Transduction; Cell Biology

Applications:ELISA

Target_protein:ADAMTS6

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.55ng/mL

Detection range:1-400ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:A Disintegrin and Metalloproteinase with Thrombospondin Motifs 6

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9UKP5

MASS(Da):125,273

GeneID:11174

Synonyms:A disintegrin and metalloproteinase with thrombospondin motifs 6;ADAM-TS 6;ADAMTS6;ADAMTS-6;ADAM-TS6

Gene names:ADAMTS6

Standard solution:480ng/mL