Human 26S Proteasome Non-atpase Regulatory Subunit 4, PSMD4 ELISA Kit

SKU: E4874Hu

Size:96 Tests-1 Kit

Background:Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMD4 acts as an ubiquitin receptor subunit through ubiquitin-interacting motifs and selects ubiquitin-conjugates for destruction. Displays a preferred selectivity for longer polyubiquitin chains.

Research_area:Cell Biology

Applications:ELISA

Target_protein:PSMD4

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.86ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:26S Proteasome Non-Atpase Regulatory Subunit 4

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P55036

MASS(Da):40,737

GeneID:5710

Synonyms:26S proteasome non-ATPase regulatory subunit 4;26S proteasome regulatory subunit RPN10;26S proteasome regulatory subunit S5A;AF;Antisecretory factor 1;ASF;Multiubiquitin chain-binding protein;PSMD 4;PSMD4;

Gene names:PSMD4

Standard solution:4800ng/L