Human 26S protease regulatory subunit 7,PSMC2 ELISA KIT

SKU: E3618Hu

Size:96 Tests-1 Kit

Background:Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides. {ECO:0000269|PubMed:1317798, ECO:0000269|PubMed:9295362}.

Research_area:

Applications:ELISA

Target_protein:PSMC2

Reactivity:Human

Assay type:Sandwich

Sensitivity:13.41ng/L

Detection range:25-1600ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:26S protease regulatory subunit 7

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P35998

MASS(Da):48634

GeneID:5701

Synonyms:PSMC2 MSS1

Gene names:PSMC2

Standard solution:3200ng/L