Human 14-3-3 protein beta;alpha,YWHAB ELISA KIT

SKU: E6899Hu

Size:96 Tests-1 Kit

Background:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13. {ECO:0000269|PubMed:17717073, ECO:0000269|PubMed:19592491, ECO:0000269|PubMed:21224381}.

Research_area:

Applications:ELISA

Target_protein:YWHAB

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.66ng/ml

Detection range:3.75-240ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:14-3-3 protein beta;alpha

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P31946

MASS(Da):28082

GeneID:7529

Synonyms:YWHAB

Gene names:YWHAB

Standard solution:480ng/ml