HSPB8 Antibody - Cat. #: CSB-PA141533

SKU: CSB-PA141533

Size :50ul

Clone Number:

Aliases:Alpha crystallin C chain antibody; Alpha-crystallin C chain antibody; Charcot Marie Tooth disease axonal type 2L antibody; Charcot Marie Tooth disease spinal antibody; CMT2L antibody; CRYAC antibody; DHMN 2 antibody; DHMN2 antibody; E2 induced gene 1 protein antibody; E2-induced gene 1 protein antibody; E2IG1 antibody; H11 antibody; Heat shock 22kDa protein 8 antibody; Heat shock 27kDa protein 8 antibody; Heat shock protein 22 antibody; Heat shock protein beta 8 antibody; Heat shock protein beta-8 antibody; Hereditary motor neuropathy distal antibody; HMN 2 antibody; HMN2 antibody; HMN2A antibody; HSB8 antibody; HSPB 8 antibody; HspB8 antibody; HSPB8_HUMAN antibody; OTTHUMP00000239768 antibody; Protein kinase H11 antibody; Small stress protein like protein HSP22 antibody; Small stress protein-like protein HSP22 antibody; Spinal muscular atrophy distal adult autosomal dominant antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UJY1

Immunogen:Fusion protein of Human HSPB8

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:HSPB8

Research Areas:Neuroscience;Signal transduction