Horse equine Endothelin ELISA Kit PicoKine®

SKU: EK0945-EQ

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Equine

Applications: ELISA

Application Details:

Gene Name: Endothelin

Specificity:

Background: The endothelins is a family of structurally and pharmacologically distinct peptides, which has been identified and sequenced in humans. Three isoforms of horse equine endothelin have been identified: endothelin-1, -2, and -3. Endothelin-1 is a potent, 21-amino acid vasoconstrictor peptide produced by vascular endothelial cells. Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium having a key role in vascular homeostasis. Endothelins are implicated in vascular diseases of several organ systems, including the heart, general circulation and brain. Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure (hypertension) and heart disease.

Immunogen: A peptide reflecting the target protein in horse equine. Sequence: C53-W73

Clonality:

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Reconstitution:

Reference:

Uniprot ID: F7APB1, Q867D0, F7AE96

Host:

Concentration:

Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

Phospho_site:

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Calculated Molecular Weight:

Gene ID: 100034060, 100033847, 100034064

Protein Name:

Gene Full Name: endothelin 1, endothelin 2, endothelin 3

Synonyms: Big endothelin 1; ET1; HDLCQ7; PPET1; Preproendothelin 1; EDN2; EDN2_HUMAN; Endothelin 2; Endothelin-2; ET 2; ET-2; ET2; PPET2; Preproendothelin 2; Preproendothelin-2; EDN3; EDN3_HUMAN; Endothelin-3; ET 3; ET-3; PPET3; Preproendothelin 3; Preproendothelin-3