HNMT antibody , Cat. # FNab03944

SKU: FNab03944

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)

Background:In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Immunogen:histamine N-methyltransferase

Synonyms:HMT

Observed MW:27 kDa

Uniprot ID:P50135

Reactivity:Human, Mouse

Tested Application:ELISA, WB, IHC, IP

Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP : 1:20 - 1:50

Gene ID:3176

Research Area:Metabolism