HIF1 alpha Polyclonal Antibody

SKU: E-AB-11289

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: HIF1A

Target Synonym: ARNT interacting protein;ARNT-interacting protein;Basic helix loop helix PAS protein MOP1;Basic-helix-loop-helix-PAS protein MOP1;bHLHe78;Class E basic helix-loop-helix protein 78;HIF 1A;HIF 1alpha;HIF-1-alpha;HIF1 A;HIF1 Alpha;HIF1;HIF1-alpha;HIF1A;HIF1A;Hypoxia inducible factor 1 alpha;Hypoxia inducible factor 1 alpha isoform I.3;Hypoxia inducible factor 1 alpha subunit;Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor;Hypoxia inducible factor 1;alpha subunit (basic helix loop helix transcription factor);Hypoxia inducible factor1alpha;Hypoxia-inducible factor 1-alpha;Member of PAS protein 1;Member of PAS superfamily 1;Member of the PAS Superfamily 1;MOP 1;MOP1;PAS domain-containing protein 8;PASD 8;PASD8

Research Areas: Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q16665

Accession:

Background: This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Concentration: 0.6 mg/mL

Immunogen: Recombinant protein of human HIF1A

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: