GSTM1 Polyclonal Antibody

SKU: D-AB-10378L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:GSTM1

Target Synonym:Glutathione S-transferase Mu 1;EC:2.5.1.18;GST 1-1;GST class-mu 1;Glutathione S-transferase GT8.7;pmGT10;Gstm1

Research Areas:

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC;IF

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P10649

Accession:

Background:Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present,eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha,kappa,mu,omega,pi,sigma,theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds,including carcinogens,therapeutic drugs,environmental toxins and products of oxidative stress,by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers,likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

Concentration:1 mg/mL

Immunogen:Recombinant Mouse GSTM1 protein expressed by E.coli

Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method:Antigen Affinity Purification

Dilution:WB 1:500-1:1000;IHC 1:300-1:600;IF 1:50-1:200

Calculated MW:25kDa

ObservedMW:26kDa