GRPR Polyclonal Antibody

SKU: E-AB-12444

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:GRPR

Target Synonym:BB2;Bombesin BB2 receptor;bombesin receptor 2;Gastrin Releasing Peptide Receptor;Gastrin-releasing peptide receptor;GRP preferring bombesin receptor;GRP R;GRP-preferring bombesin receptor;GRP-R;Grp/bombesin receptor;Grpr;GRPR

Research Areas:Cancer;Neuroscience;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P30550

Accession:

Background:Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.

Concentration:1.1 mg/mL

Immunogen:Synthetic peptide of human GRPR

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:200-1:1000;IHC 1:50-1:200

Calculated MW:43kDa

ObservedMW: