GRK2 Polyclonal Antibody

SKU: E-AB-15703

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: ADRBK1

Target Synonym: ADRBK1;Adrenergic beta receptor kinase 1;ARBK1;BARK;BARK1;Beta adrenergic receptor kinase 1;Beta ARK 1;Beta ARK1;Beta-adrenergic receptor kinase 1;Beta-ARK-1;FLJ16718;G protein coupled receptor kinase 2;G-protein coupled receptor kinase 2;GRK2

Research Areas: Cancer;Neuroscience;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P25098

Accession:

Background: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

Concentration: 0.5 mg/mL

Immunogen: Synthetic peptide of human ADRBK1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:100-1:300

Calculated MW:

ObservedMW: