GRB10 Antibody - Cat. #: CSB-PA449091

SKU: CSB-PA449091

Size :50ul

Clone Number:

Aliases:grb 10 antibody; GRB IR antibody; grb-10 antibody; GRB10 adapter protein antibody; GRB10 adaptor protein antibody; GRB10 antibody; GRB10_HUMAN antibody; GRBIR antibody; Growth factor receptor bound protein 10 antibody; Growth factor receptor-bound protein 10 antibody; Insulin receptor binding protein antibody; Insulin receptor binding protein GRB IR antibody; Insulin receptor-binding protein Grb-IR antibody; IRBP antibody; KIAA0207 antibody; Maternally expressed gene 1 antibody; MEG1 antibody; RSS antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13322

Immunogen:Synthetic peptide of Human GRB10

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:1000-1:10000, IHC:1:25-1:100

Background:The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GRB10

Research Areas:Signal transduction