GPR143 Antibody, FITC conjugated - Cat. #: CSB-PA009758LC01HU

SKU: CSB-PA009758LC01HU

Size :50ug

Clone Number:

Aliases:ALBINISM OCULAR TYPE I antibody; G protein coupled receptor 143 antibody; G-protein coupled receptor 143 antibody; GP143_HUMAN antibody; GPR143 antibody; MOA1 antibody; NETTLESHIP FALLS TYPE OCULAR ALBINISM antibody; Ocular albinism type 1 protein antibody; Ocular albinism type 1 protein homolog antibody; Ocular albinism1 Nettleship Falls type antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P51810

Immunogen:Recombinant Human G-protein coupled receptor 143 protein (314-404AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimulates Ca(2+) influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane; this ligand-dependent signaling occurs through a G(q)-mediated pathway in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Plays also a role as an intracellular G protein-coupled receptor involved in melanosome biogenesis, organization and transport.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GPR143

Research Areas:Neuroscience