GPC1 Antibody, HRP conjugated - Cat. #: CSB-PA009703LB01HU

SKU: CSB-PA009703LB01HU

Size :50ug

Clone Number:

Aliases:FLJ38078 antibody; glypican antibody; Glypican proteoglycan 1 antibody; glypican1 antibody; GPC 1 antibody; Gpc1 antibody; GPC1_HUMAN antibody; Secreted glypican-1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P35052

Immunogen:Recombinant Human Glypican-1 protein (342-530AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GPC1

Research Areas:Neuroscience; Cancer; Signal transduction