GNRHR Polyclonal Antibody

SKU: E-AB-12492

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:GNRHR

Target Synonym:GnRH receptor;GnRH-R;GNRHR;GNRHR;GNRHR1;Gonadotropin releasing hormone receptor;gonadotropin-releasing hormone (type 1) receptor 1;Gonadotropin-releasing hormone receptor;GRHR;HH7;leutinizing-releasing hormone receptor;lh-rh;LHRHR;LRHR;luliberin receptor;luteinizing hormone releasing hormone receptor;type I GnRH receptor

Research Areas:Cancer;Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P30968

Accession:

Background:This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.

Concentration:0.3 mg/mL

Immunogen:Synthetic peptide of human GNRHR

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:28kDa

ObservedMW: