GLI1 Polyclonal Antibody

SKU: E-AB-19459

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:GLI1

Target Synonym:Gli 1;GLI;GLI family zinc finger 1;GLI Kruppel family member 1;gli1;GLI1;Glioma associated oncogene 1;Glioma associated oncogene homolog 1 (zinc finger protein);Glioma associated oncogene homolog;Glioma-associated oncogene;Oncogene GLI;Zfp 5;Zfp5;Zinc finger protein GLI 1;Zinc finger protein GLI1

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Neuroscience;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P08151

Accession:

Background:GLI1 (GLI Family Zinc Finger 1) is a Protein Coding gene. Diseases associated with GLI1 include Basal Cell Carcinoma and Necrobiosis Lipoidica. Among its related pathways are Wnt Signaling Pathways: beta-Catenin-independent Wnt/Ca2+ Signaling and Other Non-canonical Wnt Signaling Pathways and G-Beta Gamma Signaling. GO annotations related to this gene include chromatin binding and microtubule binding. An important paralog of this gene is GLI2. This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration:1.08 mg/mL

Immunogen:Synthetic peptide of human GLI1

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:WB 1:500-1:2000;IHC 1:50-1:100

Calculated MW:118 kDa

ObservedMW:Refer to figures