gH Antibody - Cat. #: CSB-PA319015LA01HWV

SKU: CSB-PA319015LA01HWV

Size :50ug

Clone Number:

Aliases:gH antibody; UL75 antibody; Envelope glycoprotein H antibody; gH antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human) cytomegalovirus

UniProt ID:P12824

Immunogen:Recombinant Human cytomegalovirus Envelope glycoprotein H protein (24-195AA)

Raised in:Rabbit

Species Reactivity:Human cytomegalovirus

Tested Applications:ELISA

Background:The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis (By similarity). In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA. The gH-gL-UL128-UL130-UL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2 (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:gH

Research Areas:Others