Genome polyprotein Antibody, HRP conjugated - Cat. #: CSB-PA714772LB01HYH

SKU: CSB-PA714772LB01HYH

Size :50ug

Clone Number:

Aliases:antibody; Genome polyprotein [Cleaved into: P1; Capsid protein VP0 antibody; VP4-VP2); Capsid protein VP4 antibody; P1A antibody; Virion protein 4); Capsid protein VP2 antibody; P1B antibody; Virion protein 2); Capsid protein VP3 antibody; P1C antibody; Virion protein 3); Capsid protein VP1 antibody; P1D antibody; Virion protein 1); P2; Protease 2A antibody; P2A antibody; EC 3.4.22.29 antibody; Picornain 2A antibody; Protein 2A); Protein 2B antibody; P2B); Protein 2C antibody; P2C antibody; EC 3.6.1.15); P3; Protein 3AB; Protein 3A antibody; P3A); Viral protein genome-linked antibody; VPg antibody; Protein 3B antibody; P3B); Protein 3CD antibody; EC 3.4.22.28); Protease 3C antibody; EC 3.4.22.28 antibody; Picornain 3C antibody; P3C); RNA-directed RNA polymerase antibody; RdRp antibody; EC 2.7.7.48 antibody; 3D polymerase antibody; 3Dpol antibody; Protein 3D antibody; 3D)] antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human) enterovirus 71

UniProt ID:Q66478

Immunogen:Recombinant Human enterovirus 71 Genome polyprotein protein (566-862AA)

Raised in:Rabbit

Species Reactivity:Human enterovirus 71

Tested Applications:ELISA

Background:Capsid protein VP1: Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. Capsid protein VP1 mainly forms the vertices of the capsid. Capsid protein VP1 interacts with host cell receptor to provide virion attachment to target host cells. This attachment induces virion internalization. Tyrosine kinases are probably involved in the entry process. After binding to its receptor, the capsid undergoes conformational changes. Capsid protein VP1 N-terminus (that contains an amphipathic alpha-helix) and capsid protein VP4 are externalized. Together, they shape a pore in the host membrane through which viral genome is translocated to host cell cytoplasm. After genome has been released, the channel shrinks.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:

Research Areas:Others