GCKR Antibody - Cat. #: CSB-PA276533

SKU: CSB-PA276533

Size :100ul

Clone Number:

Aliases:FGQTL5 antibody; GCK antibody; GCKR antibody; GCKR_HUMAN antibody; GKRP antibody; GLRE antibody; glucokinase (hexokinase 4) regulator antibody; Glucokinase antibody; Glucokinase regulator antibody; Glucokinase regulatory protein antibody; Hexokinase 4 regulator antibody; Hexokinase type IV antibody; Hexokinase-4 antibody; Hexokinase-D antibody; HK IV antibody; HK4 antibody; OTTHUMP00000158533 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q14397

Immunogen:Synthesized peptide derived from internal of Human Glucokinase Regulator.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.

Warner J.P., Mamm. Genome 6:532-536(1995).
Hayward B.E., Genomics 49:137-142(1998).
Rieder M.J., Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GCKR

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction