GCG Monoclonal Antibody

SKU: BT-MCA3160

Size:100μL

Background:The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.Tissue specificity: Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain.

Research_area:Neuroscience

Target_protein:GCG

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:2F9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:GCG

Immunogen:Purified recombinant fragment of human GCG expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):21kDa

UniProt accession:P01275

Synonyms:GLP1, GLP2, GRPP, GCG

GeneID:2641