GATA1 (Ab-142) Antibody - Cat. #: CSB-PA440674

SKU: CSB-PA440674

Size :100ul

Clone Number:

Aliases:Anemia; X-linked; without thrombocytopenia; included antibody; ERYF 1 antibody; Eryf1 antibody; Erythroid transcription factor antibody; Erythrold transcription factor 1 antibody; GATA 1 antibody; GATA binding factor 1 antibody; GATA binding protein 1 (globin transcription factor 1) antibody; GATA binding protein 1 antibody; GATA-1 antibody; GATA-binding factor 1 antibody; GATA1 antibody; GATA1_HUMAN antibody; GF 1 antibody; GF-1 antibody; GF1 antibody; Globin transcription factor 1 antibody; NF E1 antibody; NF E1 DNA binding protein antibody; NF-E1 DNA-binding protein antibody; NFE 1 antibody; NFE1 antibody; Nuclear factor erythroid 1 antibody; Transcription factor GATA1 antibody; XLANP antibody; XLTDA antibody; XLTT antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P15976

Immunogen:Peptide sequence around aa.140~144 (R-L-S-P-D) derived from Human GATA1.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

Background:GATA1 encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.

Zon LI, et al. (1990) Proc Natl Acad. Sci USA. 87: 668-672.
Trainor C D, et al. (1990) Nature. 343: 92-96.
Nichols K E, et al. (2000) Nat Genet. 24: 266-270.
Freson K, et al. (2001) Blood. 98: 85-92.
Mehaffey M G, et al. (2001) Blood. 98: 2681-2688.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GATA1

Research Areas:Epigenetics and Nuclear Signaling;Developmental biology;Stem cells