GADD45B Antibody - Cat. #: CSB-PA526376

SKU: CSB-PA526376

Size :50ul

Clone Number:

Aliases:GA45B_HUMAN antibody; GADD45 Beta antibody; Gadd45b antibody; GADD45BETA antibody; Growth arrest and DNA damage inducible 45 beta antibody; Growth arrest and DNA damage inducible beta antibody; Growth arrest and DNA damage-inducible gene GADD45; beta antibody; Growth arrest and DNA damage-inducible protein GADD45 beta antibody; Growth arrest and DNA-damage-inducible protein GADD45 beta antibody; MY118 antibody; MYD118 antibody; MYD118; mouse; homolog of antibody; Myeloid differentiation primary response gene antibody; Myeloid differentiation primary response protein MyD118 antibody; Negative growth regulatory protein MyD118 antibody; Negative growth-regulatory protein MyD118 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O75293

Immunogen:Fusion protein of Human GADD45B

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GADD45B

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology;Immunology;Signal transduction