GABA A Receptor α2 rabbit pAb

SKU: ES20750

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF

Reactivity:Human;Rat;Mouse

Dilution:WB 1:1000-2000, IHC 1:100-200

Immunogen:Synthetic Peptide of GABA A Receptor α2

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):51kD

Human_gene_id:282236

Human_swiss_prot_no:P47869

Subcellular_location:Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane . Cell projection, dendrite .

Other_name:Gamma-aminobutyric acid receptor subunit alpha-2 (GABA(A) receptor subunit alpha-2)

Background:GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013],